Below are the games for Week 2 followed by the picks from our staff.
| Kenn Rashad | Kendrick Marshal | Fred Batiste | |
| September 10 | |||
| Elizabeth City St. vs. Fordham | Fordham | Fordham | Fordham |
| Californa (PA) vs Cheyney | Calif. (PA) | Calif. (PA) | Calif. (PA) |
| Lincoln (MO) vs Lincoln (PA) | Lincoln (MO) | Lincoln (PA) | Lincoln (PA) |
| Carson-Newman vs. Saint Augustine’s | Carson-Newman | SAU | SAU |
| W. Virginia State vs Urbana | W.V. State | Urbana | Urbana |
| Shaw vs. Wingate | Wingate | Wingate | Wingate |
| Prairie View vs. Texas A&M | Texas A&M | Texas A&M | Texas A&M |
| Howard vs. Rutgers | Rutgers | Rutgers | Rutgers |
| Fort Valley St. vs. Lane | Lane | Fort Valley | Fort Valley |
| Kentucky State vs. Morehouse | KSU | Morehouse | KSU |
| Tusculum vs. Virginia State | VSU | VSU | VSU |
| Edward Waters vs. Livingstone | Livingstone | Livingstone | Livingstone |
| Clark Atlanta vs. Central State | Central State | Central State | Central State |
| West Georgia vs. Miles | W. Georgia | W. Georgia | W. Georgia |
| Alabama A&M vs. Miss. Valley State | AAMU | AAMU | AAMU |
| Louisiana College vs. Texas College | La. College | La. College | La. College |
| Johnson C. Smith vs. Bowie State | Bowie State | Bowie State | Bowie State |
| Virginia Union vs. Newberry | VUU | VUU | VUU |
| Monmouth vs. Delaware St. | Monmouth | Monmouth | Mommouth |
| Albany State vs. Tuskegee | Tuskegee | Tuskegee | Tuskegee |
| Alabama St. vs. Alcorn St. | Alabama St. | Alcorn St. | Alcorn St. |
| OK Panhandle St. vs. Ark.-Pine Bluff | Okla. Panhandle | UAPB | Okla. Panhandle |
| Bethany College vs. Langston | Langston | Langston | Langston |
| SC State vs. Louisiana Tech | La. Tech | La. Tech | La. Tech |
| Bethune-Cookman vs. North Texas | North Texas | North Texas | North Texas |
| Savannah State vs. Southern Mississippi | So. Miss. | So. Miss | So. Miss. |
| Jackson State vs. Tennessee State | Tenn. State | Tenn. State | Tenn. State |
| Winston-Salem State vs. Catawba | WSSU | WSSU | WSSU |
| Campbell vs. Chowan | Chowan | Chowan | Campbell |
| William & Mary vs. Hampton | William & Mary | William &Mary | William & Mary |
| NC A&T vs. Kent State | Kent State | Kent State | Kent State |
| Morgan State vs. Marshall | Marshall | Marshall | Marshall |
| Norfolk State vs. Richmond | Richmond | Richmond | Richmond |
| Tx. Southern vs. Houston Bapt. | Tx. Southern | Tx. Southern | Houston Bapt. |
| Southern vs. Tulane | Tulane | Tulane | Tulane |
| Florida A&M vs. Coastal Carolina | CCU | CCU | CCU |
| Fayetteville St. vs. UNC Pembroke | UNCP | UNCP | UNCP |
| NC Central vs. W. Michigan | W. Mich. | W. Mich. | W. Mich. |
| Grambling vs. Arizona | Arizona | Arizona | Arizona |
