Here is the Ultimate HBCU Sports Division I Top 10 football poll after Week 10 of the regular season.
| Rank | Team | Previous rank | Record |
| 1 | Jackson State | 1 | 10-0 |
| 2 | Florida A&M | 2 | 8-2 |
| 3 | North Carolina Central | 3 | 8-2 |
| 4 | North Carolina A&T | 4 | 7-3 |
| 5 | Prairie View | 7 | 6-4 |
| 6 | Texas Southern | 8 | 5-5 |
| 7 | Southern | 9 | 6-4 |
| 8 | Alabama State | 5 | 6-4 |
| 9 | Alcorn State | 10 | 5-5 |
| 10 | Howard | NR | 4-6 |
