Here is the Ultimate HBCU Sports Division I Top 10 football poll after Week 10 of the regular season.
| Rank | Team | Previous rank | Record |
| 1 | Jackson State | 1 | 9-0 |
| 2 | Florida A&M | 3 | 7-2 |
| 3 | North Carolina Central | 4 | 7-2 |
| 4 | North Carolina A&T | 5 | 6-3 |
| 5 | Alabama State | 6 | 6-3 |
| 6 | Delaware State | NR | 5-4 |
| 7 | Prairie View | 6 | 5-4 |
| 8 | Texas Southern | 7 | 4-5 |
| 9 | Southern | 8 | 5-4 |
| 10 | Alcorn State | NR | 4-5 |
